image
GitHub Issues Notebooks Tutorials Docs
TRY THE DEMO
image
GitHub Issues Notebooks Tutorials Docs

Portable Mutational Signature Analytics

The mSigSDK enables you to have access to a powerful mutational signature analysis platform in any JavaScript environment using only a single line of code. The mSigSDK is lightweight, portable, easy-to-use, and does not require any downloads or installations. START NOW

Core Features

Mutational Burden
Signature Comparison
Indel Comparison
Signature Association
Cosine Similarity Heatmap
Dataset Summary
Prevalence of Signatures
Force Directed Tree
mSigPortal APIs mSigSDK allows developers to have programmatic access to the data APIs and interactive visualizations of mSigPortal. 
Custom Data The mSigSDK allows users to analyze their own mutation signature data by performing computations entirely in the user's browser.
TCGA Integration mSigSDK allows developers to have programmatic access to TCGA data APIs.
Interactive Visualizations mSigSDK allows users to generate over thirty different graphs for the visual analytics of mutational signature data
Signature Fitting mSigSDK has an original implementation of the non-negative least squares algorithms to allow for in-browser computation of signature exposures. 
AI Benchmarking mSigSDK automates benchmarking by allowing for the automatic training and fitting of mutational signature data to machine learning models

Try It Out

Try using the SDK in your browser's developer console
  • 1) Navigate to any website that has not blocked module loading (i.e.  https://dceg.cancer.gov/)
  • 2) Use Fn + F12 to open your browser's developer console 
  • 3) Fetch the SDK by typing the following code into the console 
    mSigSDK = (await import("https://episphere.github.io/msig/main.js")).mSigSDK
  • 4) Fetch some data from mSigPortal by typing the following code into the console: 
    data = await mSigSDK.mSigPortal.mSigPortalData.getMutationalSpectrumData()

Getting Started

Explore the features of mSigSDK 

Primary Data Sources

Explore the resources supported by mSigSDK 

mSigPortal

mSigPortal, a web-based tool for exploring and analyzing mutational signatures in cancer. It provides various modules for users to perform different tasks related to mutational signatures Learn more

Upload Your Own Data

The mSigSDK allows users to analyze their own mutation signature data by performing computations entirely in the user's browser.

Learn more

TCGA

The GDC Data Portal is a robust data-driven platform that allows cancer researchers and bioinformaticians to search and download cancer data for analysis. Learn more

Get in touch

Send us a message
Shady Grove, Maryland
9609 Medical Center Dr, Rockville, MD 20850
age1@som.umaryland.edu
(800) 422-6237
Copyright, 2021