tutorial] Individual polygenic risk score calculation (PRS) for 23andme reports, using the PGS Catalog.Privacy notice: All data and calculations take place in the browser. No data or calculations circulate by a server. This application is, foremost, an exercise in privacy-preserving biomedical informatics for consumer genomics data. Scope/Limitations:This calculator was devised as an implementation proof of concept. It has a number of important limitations for epidemiology research and it does not meet criteria for clinical use. The current tool uses pre-imputation genotype data and thus results in a low number of SNP matches. Most important, only the relative risk model (Box 1, eq 2) is calculated, with no effort to determine absolute risk of disease. Finally, the risk calculation will only be attempted for PGS catalog entries reporting effects as beta values under "effect_weight".